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LabGenius raises $10M to use AI for protein drug discovery
LabGenius, a London-based startup applying AI and “robotic automation” to protein drug discovery, has raised $10 million in Series A funding.
The round is led by Lux Capital and Obvious Ventures, with participation from Felicis Ventures, Inovia Capital, Air Street Capital and existing investors. Also investing is Recursion Pharmaceuticals’ founder and CEO Chris Gibson, as well as Inovia Capital General Partner Patrick Pichette, who was formerly Google’s CFO.
Lux Capital’s Zavain Dar and Obvious Ventures’ Nan Li will join the LabGenius board of directors. Notably, the U.K. company’s early investors include Nathan Benaich, Torsten Reil, EF’s Matt Clifford, and Philipp Moehring, to name just a few.
“LabGenius is a full-stack protein engineering company: we combine artificial intelligence (AI), robotic automation and synthetic biology to evolve next-generation protein therapeutics,” founder and CEO Dr. James Field tells me.
“My central thesis, the thing that’s really the driving force behind the company, is the conviction that we’re entering an age in which humans will no longer be the sole agents of innovation. Instead, new knowledge, technologies and sophisticated real-world products will be invented by smart robotic platforms called empirical computation engines. An empirical computation engine is an artificial system capable of recursively and intelligently searching a solution space.”
LabGenius’ flagship technology is called “EVA,” which Field describes as a “machine learning-driven, robotic platform” capable of evolving new proteins. “As a smart robotic platform, EVA is capable of designing, conducting and critically learning from its own experiments,” he says.
The goal: to discover and develop new protein therapeutics that are currently hard for humans alone to find.
“For decades, scientists, engineers and technologists have dreamt of building ‘robot scientists’ capable of autonomously discovering new knowledge, technologies and sophisticated real-world products,” explains Field.
“For protein engineers, that dream has now entered the realm of possibility. The rapid pace of technological development across the fields of synthetic biology, robotic automation and ML has given us access to all the essential ingredients required to create a smart robotic platform capable of intelligently discovering novel therapeutic proteins.”
To that end, Field frames the development of EVA as a “long-term, ambitious undertaking” that he says will enable the startup to address previously unsolvable protein engineering challenges and in doing so, develop urgently needed therapeutics.
“My ultimate goal for LabGenius is to establish a fully integrated biopharmaceutical company powered by the world’s most advanced protein engineering platform,” he adds. “Quite honestly, this is a gargantuan undertaking and, while we’ve already established one of the world’s most technically sophisticated protein engineering operations, we’re only just scratching the surface of what’s possible.”
More broadly, there is a tension that many deep tech companies face, which is determining how best to develop technology that’s tightly aligned to real-world commercial needs (before running out of capital!). “For LabGenius, we’ve achieved this in a highly intentional way by undertaking a series of commercial projects of increasing complexity from the company’s earliest days,” Field says.
One on-going project is with Tillotts Pharma AG to identify and develop new drug candidates for the treatment of inflammatory bowel disease (IBD).
“Our business model is pretty simple,” says the LabGenius founder. “We use EVA to discover and characterise new drug molecules and then partner with pharma companies who can take these molecules to market. For example in a typical partner-financed early discovery program, we’ll take a project from concept to early pre-clinical stage. Typical deal structures include a blend of R&D payments, milestones & royalties.”
Meanwhile, LabGenius will use the capital to scale its team, expand the scope of its discovery platform and initiate an “internal asset development program.” The next goal is to evolve novel antibody fragments capable of treating conditions that cannot be addressed using conventional antibody formats.
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Electric vehicle charging software EV Connect raises $12 million
EV Connect, the Los Angeles-based company that sells software to manage electric vehicle charging, has raised $12 million in a Series B round led by investors Mitsui & Co. and Ecosystem Integrity Fund.
The company has raised $25 million to date.
EV Connect’s cloud-based platform has an open standard architecture that is designed to be hardware agnostic. In other words, EV Connect aims to provide a variety of hardware vendors a way to monitor, manage and maintain charging stations.
The end goal is to push the industry away from a closed and fragmented system to a more open one, according to EV Connect CEO and founder Jordan Ramer.
EV Connect has a two-tiered approach. The company provides and manages 1,000 electric vehicle charging sites through its EV Connect network. EV Connect has a smartphone app to give drivers of electric vehicles real-time access to charging station status.
Its also sells a cloud-based software platform that businesses can customize. Clients include Yahoo!, Marriott, Hilton, Western Digital, Los Angeles Metropolitan Transportation Authority and New York Power Authority.
As part of the round, Mitsui and EV Connect have agreed to develop new business models around EV charging infrastructure. EV Connect plans to work with Mitsui on various applications of EV charging to lower the cost of charging and maximize its utilization, including fleet and energy management solutions, Ramer elaborated to TechCrunch in an emailed response.
“We strongly believe that EV Connect’s infrastructure management technology accelerates the electric vehicle revolution in the energy and power industry where Mitsui has many assets and access to partners,” Kazumasa Nakai, the COO of Mitsui’s infrastructure projects business unit, said in a statement. “Our unique engineering capabilities, in conjunction with EV Connect’s cloud-based EV infrastructure, will enable us to develop new business models to solve the challenges EV infrastructure currently pose for energy management companies.”
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Databricks announces $400M round on $6.2B valuation as analytics platform continues to grow
Databricks is a SaaS business built on top of a bunch of open-source tools, and apparently it’s been going pretty well on the business side of things. In fact, the company claims to be one of the fastest growing enterprise cloud companies ever. Today the company announced a massive $400 million Series F funding round on a hefty $6.2 billion valuation. Today’s funding brings the total raised to almost a $900 million.
Andreessen Horowitz’s Late Stage Venture Fund led the round with new investors BlackRock, Inc., T. Rowe Price Associates, Inc. and Tiger Global Management also participating. The institutional investors are particularly interesting here because as a late-stage startup, Databricks likely has its eye on a future IPO, and having those investors on board already could give them a head start.
CEO Ali Ghodsi was coy when it came to the IPO, but it sure sounded like that’s a direction he wants to go. “We are one of the fastest growing cloud enterprise software companies on record, which means we have a lot of access to capital as this fundraise shows. The revenue is growing gangbusters, and the brand is also really well known. So an IPO is not something that we’re optimizing for, but it’s something that’s definitely going to happen down the line in the not-too-distant future,” Ghodsi told TechCrunch.
The company announced as of Q3 it’s on a $200 million run rate, and it has a platform that consists of four products, all built on foundational open source: Delta Lake, an open-source data lake product; MLflow, an open-source project that helps data teams operationalize machine learning; Koalas, which creates a single machine framework for Spark and Pandos, greatly simplifying working with the two tools; and, finally, Spark, the open-source analytics engine.
You can download the open-source version of all of these tools for free, but they are not easy to use or manage. The way that Databricks makes money is by offering each of these tools in the form of Software as a Service. They handle all of the management headaches associated with using these tools and they charge you a subscription price.
It’s a model that seems to be working, as the company is growing like crazy. It raised $250 million just last February on a $2.75 billion valuation. Apparently the investors saw room for a lot more growth in the intervening six months, as today’s $6.2 billion valuation shows.
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Figma’s Community lets designers share and remix live files
As designers grow both in sheer numbers and within the hierarchy of organizations, design tool makers are adapting to their evolving needs in different ways. Figma, the web-based collaborative design tool, is taking a note from the engineering revolution of the early aughts.
“What if there were a GitHub for designers?” mused Dylan Field, early on in the lifecycle of Figma as a company. Today, that vision is brought to life with the launch of Figma Community. (Figma Community is launching in a closed beta for now.)
In a crowded space, with competitors like Adobe, InVision, Sketch and more, Figma differentiates itself on its web-based multiplayer approach. Figma is a design tool that works like Google Docs, with multiple designers in the same file, working alongside one another without disrupting each other.
But that’s just the base level of the overall collaboration that Figma believes designers crave. Field told us that he sees a clear desire from designers to not only share their work, whether it’s on a portfolio webpage or on social media, as well as a desire to learn from the work of other designers.
And yet, when a creative shares a design on social media, it’s just a static image. Other designers can’t see how it went from a blank page to an interesting design, and are left to merely appreciate it without learning anything new.
With Figma Community, designers and even organizations can share live design files that others can inspect, remix and learn from.
Individual designers can set up their own public-facing profile page to show off their designs, as well as intra-organization profile pages so other team members within their organization can learn from each other. On the other hand, organizations can publicly share their design systems and philosophy on their own page.
For example, the city of Chicago has set up a profile on Figma Community for other designers to follow the city’s design system in their own materials.
As far as remixing design files goes, Figma is using a CC4 license, which allows for a remix but forces attribution. That said, Field says the company is using this closed beta period to learn more about what the community wants around different license types.
Community is free and is not meant to drive revenue for the company, but rather offer further value to designers using the platform.
“It’s early,” said Dylan Field. “This is just the scaffolding of what’s to come. It’s the start of a lot of work that we’re going to be doing in the area of collaboration and community.”
Figma has raised a total of $83 million from investors like Index, Sequoia, Kleiner Perkins and Grelock, according to Crunchbase.
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Early-stage privacy startup DataGrail gets boost from Okta partnership
When Okta launched its $50 million Okta Ventures investment fund in April, one of its investments was in an early-stage privacy startup called DataGrail. Today, the companies announced a partnership that they hope will help boost DataGrail, while providing Okta customers with a privacy tool option.
DataGrail CEO and co-founder Daniel Barber says that with the increase in privacy legislation, from GDPR to the upcoming California Consumer Protection Act (and many other proposed bills in various states of progress), companies need tools to help them comply and protect user privacy. “We are a privacy platform focused on delivering continuous compliance for businesses,” Barber says.
They do this in a way that fits nicely with Okta’s approach to identity. Whereas Okta provides a place to access all of your cloud applications from a single place with one logon, DataGrail connects to your applications with connectors to provide a way to monitor privacy across the organization from a single view.
It currently has 180 connectors to common enterprise applications like Salesforce, HubSpot, Marketo and Oracle. It then collects this data and presents it to the company in a central interface to help ensure privacy. “Our key differentiator is that we’re able to deliver a live data map of the customer data that exists within an organization,” Barber explained.
The company just launched last year, but Barber sees similarities in their approaches. “We see clear alignment on our go-to-market approach. The product that we built aligns very similarly to the way Okta is deployed, and we’re a true partner with the industry leader in identity management,” he said.
Monty Gray, SVP and head of corporate development at Okta, says that the company is always looking for innovative companies that fit well with Okta. The company liked DataGrail enough to contribute to the startup’s $5.2 million Series A investment in July.
Gray says that while DataGrail isn’t the only privacy company it’s partnering with, he likes how DataGrail is helping with privacy compliance in large organizations. “We saw how DataGrail was thinking about [privacy] in a modern fashion. They enable these technology companies to become not only compliant, but do it in a way where they were not directly in the flow, that they would get out of the way,” Gray explained.
Barber says having the help of Okta could help drive sales, and for a company that’s just getting off the ground, having a public company in your corner as an investor, as well as a partner, could help push the company forward. That’s all that any early startup can hope for.
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Aurora Insight emerges from stealth with $18M and a new take on measuring wireless spectrum
Aurora Insight, a startup that provides a “dynamic” global map of wireless connectivity that it built and monitors in real time using AI combined with data from sensors on satellites, vehicles, buildings, aircraft and other objects, is emerging from stealth today with the launch of its first publicly available product, a platform providing insights on wireless signal and quality covering a range of wireless spectrum bands, offered as a cloud-based, data-as-a-service product.
“Our objective is to map the entire planet, charting the radio waves used for communications,” said Brian Mengwasser, the co-founder and CEO. “It’s a daunting task.” He said that to do this the company first “built a bunker” to test the system before rolling it out at scale.
With it, Aurora Insight is also announcing that it has raised $18 million in funding — an aggregate amount that reaches back to its founding in 2016 and covers both a seed round and Series A — from an impressive list of investors. Led by Alsop Louie Partners and True Ventures, backers also include Tippet Venture Partners, Revolution’s Rise of the Rest Seed Fund, Promus Ventures, Alumni Ventures Group, ValueStream Ventures and Intellectus Partners.
The area of measuring wireless spectrum and figuring out where it might not be working well (in order to fix it) may sound like an arcane area, but it’s a fairly essential one.
Mobile technology — specifically, new devices and the use of wireless networks to connect people, objects and services — continues to be the defining activity of our time, with more than 5 billion mobile users on the planet (out of 7.5 billion people) today and the proportion continuing to grow. With that, we’re seeing a big spike in mobile internet usage, too, with more than 5 billion people, and 25.2 billion objects, expected to be using mobile data by 2025, according to the GSMA.
The catch to all this is that wireless spectrum — which enables the operation of mobile services — is inherently finite and somewhat flaky in how its reliability is subject to interference. That in turn is creating a need for a better way of measuring how it is working, and how to fix it when it is not.
“Wireless spectrum is one of the most critical and valuable parts of the communications ecosystem worldwide,” said Rohit Sharma, partner at True Ventures and Aurora Insight board member, in a statement. “To date, it’s been a massive challenge to accurately measure and dynamically monitor the wireless spectrum in a way that enables the best use of this scarce commodity. Aurora’s proprietary approach gives businesses a unique way to analyze, predict, and rapidly enable the next-generation of wireless-enabled applications.”
If you follow the world of wireless technology and telcos, you’ll know that wireless network testing and measurement is an established field — about as old as the existence of wireless networks themselves (which says something about the general reliability of wireless networks). Aurora aims to disrupt this on a number of levels.
Mengwasser — who co-founded the company with Jennifer Alvarez, the CTO who you can see presenting on the company here — tells me that a lot of the traditional testing and measurement has been geared at telecoms operators, who own the radio towers, and tend to focus on more narrow bands of spectrum and technologies.
The rise of 5G and other wireless technologies, however, has come with a completely new playing field and set of challenges from the industry.
Essentially, we are now in a market where there are a number of different technologies coexisting — alongside 5G we have earlier network technologies (4G, LTE, Wi-Fi); and a potential set of new technologies. And we have a new breed of companies building services that need to have close knowledge of how networks are working to make sure they remain up and reliable.
Mengwasser said Aurora is currently one of the few trying to tackle this opportunity by developing a network that is measuring multiples kinds of spectrum simultaneously, and aims to provide that information not just to telcos (some of which have been working with Aurora while still in stealth) but the others kinds of application and service developers that are building businesses based on those new networks.
“There is a pretty big difference between us and performance measurement, which typically operates from the back of a phone and tells you when have a phone in a particular location,” he said. “We care about more than this, more than just homes, but all smart devices. Eventually, everything will be connected to network, so we are aiming to provide intelligence on that.”
One example are drone operators that are building delivery networks: Aurora has been working with at least one while in stealth to help develop a service, Mengwasser said, although he declined to say which one. (He also, incidentally, specifically declined to say whether the company had talked with Amazon.)
5G is a particularly tricky area of mobile network spectrum and services to monitor and tackle, which is one reason why Aurora Insight has caught the attention of investors.
“The reality of massive MIMO beamforming, high frequencies, and dynamic access techniques employed by 5G networks means it’s both more difficult and more important to quantify the radio spectrum,” said Gilman Louie of Alsop Louie Partners, in a statement. “Having the accurate and near-real-time feedback on the radio spectrum that Aurora’s technology offers could be the difference between building a 5G network right the first time, or having to build it twice.” Louie is also sitting on the board of the startup.
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Todoist releases major update to simplify task management
Bootstrapped tech company Doist, the company behind popular task management Todoist, is releasing a major update called Todoist Foundations — the update should be rolled out over the next 24 hours. As the name suggests, it lays foundations for many new features down the road.
But there are already some interesting improvements. Task lists in Todoist don’t have to be an endless list of checkboxes anymore. You can now create sections in your projects. You can then move tasks from one section to another, and collapse sections when you don’t need to see them.
Down the road, those sections could play a bigger role. For instance, a project could have sections representing multiple steps to achieve a task. You could imagine other views that let you move a task from one step to another.
When it comes to labels, they are now sorted in two categories — your personal labels and shared labels with other co-workers.
Todoist has also added a new task view on desktop and mobile that centralizes everything you can do related to a task. You can modify the due date and priority level, see comments, add labels and more. Even better, you can see all the subtasks associated with a specific task in this new view.
When it comes to mobile-specific improvements, the quick add bar has been overhauled. Quick add has always been one of my favorite features in Todoist. For instance, you can type “Send contract tomorrow at 9am @bestclient #work” to create a “Send contract” task in the “work” project, with a due date and the label “bestclient.”
Todoist first added buttons on mobile to surface those features and make them more intuitive. The company is simplifying the bar as it got really busy. It now displays existing due dates, projects and assignees in buttons directly. There are now fewer icons for less-important features.
Todoist also borrowed a feature from Things 3 with the plus button. You can now drag and drop the plus button anywhere in a list to add a new task in the middle of the list. That feature is incredibly useful.
Behind the scene, everything should be faster as well. Finally, Todoist updated icons and its color palette.
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Report: SoftBank is taking control of WeWork at an ~$8B valuation
WeWork, once valued at $47 billion, will be worth as little as $7.5 billion on paper as SoftBank takes control of the struggling co-working business, CNBC reports.
SoftBank, a long-time WeWork investor, plans to invest between $4 billion and $5 billion in exchange for new and existing shares, according to CNBC . The deal, expected to be announced as soon as tomorrow, represents a lifeline for WeWork, which is said to be mere weeks from running out of cash and has been shopping several of its assets as it attempts to lessen its cash burn.
WeWork declined to comment.
To be clear, it is reportedly the Vision Fund’s parent company, SoftBank Group Corp. that is taking control, with SoftBank International chief executive officer Marcelo Claure stepping in to support company management, per reports.
The Japanese telecom giant’s move comes precisely four weeks after co-founder and former CEO Adam Neumann relinquished control of the company and transitioned into a non-executive chairman role, and about three weeks after WeWork decided to delay its highly anticipated initial public offering. WeWork’s vice chairman Sebastian Gunningham and the company’s president and chief operating officer Artie Minson are currently serving as WeWork’s co-CEOs.
In addition to those personnel shake-ups, WeWork has lost its communications chief, Jimmy Asci, its chief marketing officer, Robin Daniels and several others. Meanwhile, the company has slashed hundreds of jobs, and opted to shut down its school, WeGrow, in 2020.
Now expected to go public in 2020, WeWork was also said to be in negotiations with JPMorgan for a last-minute cash infusion. The company, now a cautionary tale, will surely continue to reduce the sky-high costs of its money-losing operation in the upcoming months.
WeWork revealed an unusual IPO prospectus in August after raising more than $8 billion in equity and debt funding. Despite financials that showed losses of nearly $1 billion in the six months ending June 30, the company still managed to accumulate a valuation as high as $47 billion, largely as a result of Neumann’s fundraising abilities.
“As co-founder of WeWork, I am so proud of this team and the incredible company that we have built over the last decade,” Neumann said in a statement confirming his resignation last month. “Our global platform now spans 111 cities in 29 countries, serving more than 527,000 members each day. While our business has never been stronger, in recent weeks, the scrutiny directed toward me has become a significant distraction, and I have decided that it is in the best interest of the company to step down as chief executive. Thank you to my colleagues, our members, our landlord partners, and our investors for continuing to believe in this great business.”
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Is there room for a US equivalent to China’s No. 1 news app?
In China, Toutiao is literally big news.
Not only has its parent company ByteDance achieved a $75 billion valuation, two of its apps — Toutiao, a news aggregator, and Douyin (Tik Tok in China) — are chipping into WeChat’s user engagement numbers, no small feat considering the central role WeChat plays in the daily lives of the region’s smartphone users.
The success of Toutiao (its name means “headline”) prompts the question: why hasn’t one news aggregator app achieved similar success in the United States? There, users can pick from a roster of news apps, including Google News, Apple News (on iOS), Flipboard, Nuzzel and SmartNews, but no app is truly analogous to Toutiao, at least in terms of reach. Many readers still get news from Google Search (not the company’s news app) and when they do use an app for news, it’s Facebook.
The top social media platform continues to be a major source of news for many Americans, even as they express reservations about the reliability of the content they find there. According to research from Columbia Journalism Review, 43% of Americans use Facebook and other social media platforms to get news, but 57% said they “expect the news they see on those platforms to be largely inaccurate.” Regardless, they stick with Facebook because it’s timely, convenient and they can share content with friends and read other’s comments.
The social media platform is one of the main reasons why no single news aggregator app has won over American users the same way Toutiao has in China, but it’s not the only one. Other factors, including differences between how the Internet developed in each country, also play a role, says Ruiwan Xu, the founder and CEO of CareerTu, an online education platform that focuses on data analytics, digital marketing and research.
While Americans first encountered the Internet on PCs and then shifted to mobile devices, many people in China first went online through their smartphones and the majority of the country’s 800 million Internet users access it through mobile. This makes them much more open to consuming content — including news and streaming video — on mobile.
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Superhuman founder seeks to raise debut venture fund
The founder of one of 2019’s most buzzworthy startups is putting on his VC hat.
Rahul Vohra, the creator of the $30/month subscription emailing service Superhuman, and Todd Goldberg, the founder of the marketing business Mailjoy, are circulating a pitch deck to potential limited partners, with plans to raise a $4 million debut angel fund, TechCrunch has learned.
Goldberg declined to comment. Vohra did not respond to a request for comment.
San Francisco-based Superhuman has raised millions in venture capital funding, attracting a $260 million valuation with a $33 million investment led by the respected firm Andreessen Horowitz earlier this year. Quickly, Superhuman developed a loyal fan base and inspired a new wave of startups building for the “prosumer.”
“Superhuman has become an aspirational brand and product that many SaaS companies want to emulate,” Vohra and Goldberg write in the deck, obtained by TechCrunch. “Founders of these companies seek out Rahul as an investor. This helps us get into the hottest rounds — even the closed ones.”
Vohra and Goldberg have been seeding startups for the past four years, according to the deck. Both men have completed the Y Combinator startup accelerator and funded other graduates of the program, including Tandem, which emerged from YC this summer with funding from a16z, Vohra and several others. One or both of the pair have also invested in Command E, a tool that enables instant cloud search; Mercury, a bank tailored to the needs of startups; and Sandbox VR, which is developing premium virtual reality experiences in retail locations.
Many of Vohra and Goldberg’s existing investments, such as Sandbox VR, Tandem and Mercury, are also a16z portfolio companies, as is Superhuman. We’re guessing Vohra has served as a sort of scout for the firm, bringing in attractive deals for a16z to lead, with room for him to nab a friendly allocation.
Vohra and Goldberg are hoping to collect capital from LPs to scale their investment activity. According to the deck, they will make 25 to 35 deals with check sizes ranging between $50,000 to $150,000. The fund will invest in the “prosumerization” of the enterprise, business infrastructure, health, fitness & wellness, “devsumer” & low-code/no-code, audio-first products, creator tools and “enterprization” of consumers.
Indeed, the deck is packed with buzzwords. The “prosumerization” of the enterprise is tech-speak for work products with nicer interfaces and more premium features. A “devsumer” tool is one that enables consumers to complete developer tasks on their own, i.e. without coding — devsumer products on the market include Airtable, Notion and Retool. Finally, the “enterprization” of consumers simply means the rise of business tools built for consumers first.
Vohra and Goldberg cite their experience as operators as one of their “unfair advantages,” along with their ability to secure large allocations (a decent piece of the pie) in startups, their YC network, relationships with other angels & funds and their ability to get pro rata access in later rounds.
Founders often search for established operators to join their cap tables for exactly these reasons. Someone like Vohra can help startups foster relationships with big-name venture capital backers and make critical introductions to their own rapidly growing pool of customers.
The rise of micro-funds led by networked entrepreneurs, including Niv Dror’s Shrug Capital or Brianne Kimmel’s new outfit, Work Life Ventures, for example, could pose a threat to existing institutional seed investors, who may not be as well-versed in specific sectors or able to offer as much time to potential founders. On the other hand, many micro-funds co-invest with or are backed by VCs, which means returns from the fund end up in the same pockets, in essence.
Deploying capital from a fund, however, is time consuming. How Vohra can balance building a Series B startup and investing in upwards of 35 businesses remains to be seen.
Though Superhuman was founded in 2014 — Vohra incorporated the business immediately after the LinkedIn acquisition of his previous startup, Rapportive — the company is essentially still in closed beta (those looking for access must be approved for the service in iOS’s TestFlight, where constant beta updates are delivered). Today, it’s popular in the Bay Area tech scene where the tagline “sent via Superhuman” has become a status symbol of sorts. But many are uncertain non-techies will be willing to shell out $30 per month for a luxury email tool.
With that said, Superhuman has a wait list of 180,000 people, according to The New York Times, which spoke to Vohra in June. With a large and growing valuation, an email tool with rave reviews and a set of loyal followers, Vohra will likely have no trouble navigating his way into Silicon Valley’s hottest deals.
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